Monthly Archives: May 2012

Typhlitis

Typhlitis, also known as necrotizing enterocolitis, is a devastating infection that can affect those with hematologic malignancies after receiving chemotherapy.  It usually occurs when the patient is neutropenic and the mortality is high.  This condition was previously thought to affect … Continue reading

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Sickle Cell Disease: Acute Chest Syndrome

Sickle cell disease (SCD) refers to the different genotypes that cause characteristic clinical syndromes. It is an autosomal recessive genetic blood disorder consisting of a valine substitution for glutamic acid at the sixth position of the B-globin chain. Sickle-cell anemia … Continue reading

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Hemophilia

Hemophilia A and B are sex-linked (X chromosome) recessive disorders. Hemophilia A is a clotting factors VIII (FVIII) deficiency affecting one in every 5,000–10,000 male births. Hemophilia B is a clotting factor IX (FIX) deficiency which has a an occurrence … Continue reading

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Superior Vena Cava Syndrome

Superior Vena Cava Syndrome (SVCS) is caused by lung cancer, especially small cell, and lymphoma in approximately 90% of cases. A minority of cases are caused by fibrosing mediastinitis and thrombosis of indwelling central venous devices. Syphilitic aortic aneurysm and … Continue reading

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